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Clinical and Experimental Obstetrics & Gynecology  2017, Vol. 44 Issue (4): 509-510    DOI: 10.12891/ceog3881.2017
Original Research Previous articles | Next articles
Successful pregnancy following in vitro fertilization-embryo transfer in a woman with diminished oocyte reserve despite a slow rising beta human chorionic gonadotropin level
J. H. Check1, 2, *(), R. Chern2, E. Chang2
1 Cooper Medical School of Rowan University, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Camden, NJ, USA
2 Cooper Institute for Reproductive and Hormonal Disorders, P.C., Mt. Laurel, NJ, USA
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Abstract  Purpose: To present another rare case of a live pregnancy despite an inappropriate rising serum beta hCG level. Materials and Methods: A woman with diminished oocyte reserve had an in vitro fertilization (IVF) cycle, so the precise day of ovulation was known. Results: Despite an inappropriate doubling time for the serum beta-hCG level and a crown rump length sac size discrepancy (small sac), an apparently healthy fetus with no apparent anomalies has passed the second trimester. Conclusions: Despite the risk of ectopic pregnancies with slow rising hCG levels, and the generally very low chance of a successful viable pregnancy, one may need to not be too quick to terminate the pregnancy with methotrexate.
Key words:  Slow rising beta-hCG      Viable pregnancy      Small gestational sac      Diminished oocyte reserve      Methotrexate     
Published:  10 August 2017     
*Corresponding Author(s):  J.H. CHECK     E-mail:  laurie@ccivf.com

Cite this article: 

J.H. Check, R. Chern, E. Chang. Successful pregnancy following in vitro fertilization-embryo transfer in a woman with diminished oocyte reserve despite a slow rising beta human chorionic gonadotropin level. Clinical and Experimental Obstetrics & Gynecology, 2017, 44(4): 509-510.

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https://ceog.imrpress.com/EN/10.12891/ceog3881.2017     OR     https://ceog.imrpress.com/EN/Y2017/V44/I4/509

[1] J.H. Check, D. Summers, D. Horwath, J.K. Choe. Preimplantation genetic diagnosis for a single gene mutation for succinate dehydrogenase subunit B (the genetic basis for malignant paraganglioma) with successful pregnancy[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(3): 473-475.
[2] M. Meléndez Zalduegui, S. Iglesias Ferreiro, A. Rodríguez Vélez, ML. Monje Beltrán, EM. Vicedo Madrazo, RJ. Martínez Portillo, M. Llobet Roma, M. Marqueta Sánchez. Cesarean scar ectopic pregnancy, a life threatening condition: a case report[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(2): 313-316.
[3] J.H. Check. The pros and cons of the requirement by the Society for Assisted Reproductive Technology (SART) for their members who perform in vitro fertilization and related procedures to report their pregnancy rates to the center for disease control[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(2): 155-158.
[4] R.C. Drăguşin, M. Șorop-Florea, C. Constantin, Ş. Tudorache, N. Cernea, D.G. Iliescu. Management of uncomplicated interstitial pregnancy with systemic methotrexate and uterine artery embolization. Case report[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(2): 290-291.
[5] G. Garuti, S. Calabrese, G. Baudino, C. Reato, L. Quirino, M. Di Mario. Hysteroscopic removal of cesarean scar pregnancy after primary therapy with methotrexate: a case series[J]. Clinical and Experimental Obstetrics & Gynecology, 2017, 44(6): 856-861.
[6] B. Bechev, M. Konovalova. A very rare case of ectopic intramural pregnancy after IVF-ET[J]. Clinical and Experimental Obstetrics & Gynecology, 2017, 44(5): 802-803.
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