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Clinical and Experimental Obstetrics & Gynecology  2017, Vol. 44 Issue (5): 710-715    DOI: 10.12891/ceog3744.2017
Original Research Previous articles | Next articles
Uterus and myoma histomorphology
İ. Ceylan1, T. Peker2, *(), N. Coşkun3, S. Ömeroğlu3, A. Poyraz4
1 Ankara University, Institute of Health, Neuroscience Department, Sihhiye, Ankara, Turkey
2 Department of Anatomy, Faculty of Medicine, Gazi University, Beşevler, Ankara, Turkey
3 Department of Histology and Embryology, Faculty of Medicine, Gazi University, Beşevler, Ankara, Turkey
4 Department of Pathology, Faculty of Medicine, Gazi University, Beşevler, Ankara, Turkey
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Abstract  
Objective: Uterine fibroids, or leiomyomas are common benign neoplasms of the myometrium. These neoplasms are composed of large amounts of extracellular matrix and disarrayed smooth muscle tissue. The aim of this study was to examine the histomorphological differences between myoma uteri and uterus. Materials and Methods: Thickness of muscle fascicles and collagen fibers, and vascular and histological structures were evaluated by using morphometric, histomorphologic and immunohistochemical analyses, and findings represented by using three-dimensional (3D) modeling. The authors used a light microscope and photos were captured using a specific program for analysis. Light micrographs were assembled into 3D images. Results and Conclusion: Histological and 3D findings demonstrated that the muscle fiber is a vital part of the myometrium and loss of its contractility indicates a significant deviation from the uterine structure.
Key words:  Histomorphology      Immunohistochemistry      Three-dimensional modeling      Uterine myoma      Uterus      Leiomyomas     
Published:  10 October 2017     
*Corresponding Author(s):  T. PEKER     E-mail:  tpeker@gazi.edu.tr

Cite this article: 

İ. Ceylan, T. Peker, N. Coşkun, S. Ömeroğlu, A. Poyraz. Uterus and myoma histomorphology. Clinical and Experimental Obstetrics & Gynecology, 2017, 44(5): 710-715.

URL: 

https://ceog.imrpress.com/EN/10.12891/ceog3744.2017     OR     https://ceog.imrpress.com/EN/Y2017/V44/I5/710

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[4] Ş. Gezer, B. Vural. Double cervix, septate uterus, and longitudinal vaginal septum: a rare Müllerian anomaly with leiomyoma of the uterus[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(4): 648-650.
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[10] K. Kai, Y. Kai, M. Nishida, K. Nasu, S. Iwanaga, H. Narahara. Modified Gilliam-Doleris hysteropexy for juvenile uterovaginal prolapse[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(1): 109-111.
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