Please wait a minute...
Clinical and Experimental Obstetrics & Gynecology  2017, Vol. 44 Issue (3): 429-433    DOI: 10.12891/ceog3607.2017
Original Research Previous articles | Next articles
The prevalence of abnormal vaginal flora and predictive factors for intrauterine infection in pregnant Korean women with preterm labor
Kwan Young Oh1, *(), Chan Hee Jin1, Yong Hak Sohn2, Hyun A. Cho3, Moran Ki4
1 Department of Obstetrics and Gynecology, College of Medicine, Eulji University, Daejeon, Republic of Korea
2 Department of Laboratory Medicine, College of Medicine, Eulji University, Daejeon, Republic of Korea
3 Department of Occupational Environmental Medicine, College of Medicine, Eulji University, Daejeon, Republic of Korea
4 Department of Cancer Control and Policy, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Republic of Korea
Download:  PDF
Export:  BibTeX | EndNote (RIS)      
Abstract  Objective: To investigate the prevalence of abnormal vaginal flora (AVF) and predictive factors for intrauterine infection in pregnant Korean women with preterm labor. Materials and Methods: The authors reviewed the medical records of 106 pregnant Korean women with preterm labor admitted to Eulji Medical Center between January 2006 and August 2011. The results of vaginal discharge tests and maternal serum C-reactive protein (CRP) level at admission, placental biopsy, and perinatal outcomes were searched. The prevalence of abnormal vaginal flora was calculated. The perinatal outcomes and predictive factors for intrauterine infections were analyzed based on placental pathology and early-onset neonatal sepsis. Results: The prevalence of abnormal vaginal flora was 75.4%. Ureaplasma urealyticum (UU), intermediate flora, Candidiasis, bacterial vaginosis, and aerobic bacterial colonization were detected in 40.6%, 38.7%, 17%, 14.2%, and 11.3% of the women, respectively. The frequency of early-onset neonatal sepsis was significantly different between women with aerobic bacterial colonization and those with normal flora (p = 0.008). An elevated maternal serum CRP level was an independent intrauterine infection predictor (odds ratio, 1.918; 95% confidence interval, 1.102-3.338; p = 0.048). Conclusion: Aerobic bacterial colonization may predict early-onset neonatal sepsis. An elevated maternal serum CRP level was an independent intrauterine infection predictor based on placental infections and early-onset neonatal sepsis.
Key words:  Maternal serum C-reactive protein level      Spontaneous preterm labor      Pregnancy      Microorganisms      Predictor     
Published:  10 June 2017     
*Corresponding Author(s):  KWAN YOUNG. OH     E-mail:  ohky5@eulji.ac.kr

Cite this article: 

Kwan Young Oh, Chan Hee Jin, Yong Hak Sohn, Hyun A. Cho, Moran Ki. The prevalence of abnormal vaginal flora and predictive factors for intrauterine infection in pregnant Korean women with preterm labor. Clinical and Experimental Obstetrics & Gynecology, 2017, 44(3): 429-433.

URL: 

https://ceog.imrpress.com/EN/10.12891/ceog3607.2017     OR     https://ceog.imrpress.com/EN/Y2017/V44/I3/429

[1] H. Yolli, M.E. Demir, R. Yildizhan. Neutrophil gelatinase associated lipocalin-2 (Ngal) levels in preeclampsia[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(4): 519-523.
[2] K. Chikazawa, K. Imai, T. Kuwata, K. Takagi. Prophylactic laparoscopic adnexal surgery with low-pressure CO2 insufflation for ovarian cysts during the late first trimester or second trimester of pregnancy[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(4): 537-540.
[3] J. A. Villarreal-Rodriguez, L. G. Mancillas Adame, J. Maldonado-Sanchez, A. Guzmán-López, O. R. Treviño-Montemayor, J. G. Gonzalez-Gonzalez, D. Saldívar-Rodríguez. A randomized controlled trial comparing acarbose vs. insulin therapy for gestational diabetes in individuals with inadequate glycemic control by diet alone[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(4): 552-555.
[4] J. Ogawa, S. Suzuki. Risk factors of self-interruption of medications for mental disorders in pregnancy[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(4): 576-578.
[5] A. Daniilidis, G. Dryllis, G. Chorozoglou, M. Politou, R. Dampali, K. Dinas. Substitution of hemoglobin levels in pregnant women with iron supplement: A prospective randomized clinical study[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(4): 579-583.
[6] Z.Y. Chang, R. Cao, R.C. Xu, Y. Cheng, Q.J. Wan. Pregnancy in a peritoneal dialysis patient undergoing intermittent peritoneal dialysis during the third trimester of pregnancy: a case report and literature review[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(4): 596-599.
[7] C.Y. Huang, T.C. Chao, H.C. Chien, Y.L. Liu. Outcome of shared decision-making in a patient with primary herpes gingivostomatitis during pregnancy: a case report[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(4): 604-606.
[8] G.L. Liu, S.C. He, W.J. Shan, H.Y. Chen. Repetitive hydatidiform mole in the cesarean scar: a case report and literature review[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(4): 607-610.
[9] K. Nakanishi, Y. Oishi, T. Miyamoto, E. Nakamura, K. Murakami, M. Ono, A. Nozawa, S. Kitamura, K. Sengoku. Anti-E alloimmunization in a pregnancy with a low antibody titer[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(4): 614-616.
[10] F. Wang, Z.X. Liang, W.R. Mao, S.N. He, D.Q. Chen. Influence of pre-pregnancy body mass index and gestational weight gain in twin pregnancies on blood glucose, serum lipid and perinatal outcomes[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(3): 376-382.
[11] G. Keren, G. Ayala. Factors associated with hyperemesis gravidarum[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(3): 391-395.
[12] H. Cokmez, C. Bayram. Pituitary apoplexy developing during pregnancy: escape from the verge of death[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(3): 429-431.
[13] H.J. Wang, T.H. Chou, Y.C. Lee, H.K. Au. Acute fatty liver during pregnancy and gestational diabetes insipidus: a case report[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(3): 438-441.
[14] Y.Q. Xu, X. L. Chen, S. Zhao, P. W. Chen, X. M. Yin, S. Y. Xiong, Z. Ding, F. Xiong, X. H. Yang. OEIS complex (omphalocele-exstrophy-imperforate anus-spinal defects) in monozygotic twins: a case report and literature review[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(2): 154-158.
[15] H.F. Zhang, J. Zhang, D. Yang, S.N. Li. Clinical analysis of atrial fibrillation in pregnant women[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(2): 174-178.
No Suggested Reading articles found!