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Clinical and Experimental Obstetrics & Gynecology  2016, Vol. 43 Issue (5): 759-762    DOI: 10.12891/ceog3337.2016
Original Research Previous articles | Next articles
Evaluation of ten years of intrauterine insemination results at a tertiary center
E. S. Güngör1, *(), C. Dane2
1Süleymaniye Maternity Research and Training Hospital, Istanbul
2Haseki Research and Training Hospital, Istanbul (Turkey)
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Abstract  
Purpose: To report on ten years of intrauterine insemination (IUI) practice at Haseki Training and Research Hospital to determine retrospectively, the impact of IUI on the management of subfertile couples. Materials and Methods: This study was a retrospective analysis of all IUI cycles completed from June 1, 2003, to July 1, 2013, at the Haseki Training and Research Hospital, Istanbul, Turkey. Baseline clinical characteristics, drugs used for ovulation induction, and triggering ovulation were reviewed. The primary outcome was clinical pregnancy. Results: The overall clinical pregnancy rate was 10.2% (26/253). Improved success was significantly associated with a shorter period of infertility (4.8 ± 3.9 years vs 3.2±2.4 years; p = 0.01). Clinical pregnancy rates were significantly higher when recombinant FSH was used for ovulation induction than clomiphene citrate (CC) (22% vs 5.6%; p = 0.002). Patients were also analysed for the drug used for triggering ovulation. The clinical pregnancy rate was 27.2% in the recombinant hCG group compared with 8.6% in the urinary hCG group (p = 0.006). Conclusions: IUI may be a safe and cost-effective option for mild male factor infertility or unexplained infertility. Better results may be obtained when recombinant FSH and recombinant hCG are used and when the duration of infertility is short.
Key words:  Intrauterine insemination      Clinical pregnancy rate      Ovulation induction      Ovulation triggering      Unexplained infertility     
Published:  10 October 2016     
*Corresponding Author(s):  E. S. GÜNGÖR     E-mail:  doksinangungor@hotmail.com

Cite this article: 

E. S. Güngör, C. Dane. Evaluation of ten years of intrauterine insemination results at a tertiary center. Clinical and Experimental Obstetrics & Gynecology, 2016, 43(5): 759-762.

URL: 

https://ceog.imrpress.com/EN/10.12891/ceog3337.2016     OR     https://ceog.imrpress.com/EN/Y2016/V43/I5/759

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