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Clinical and Experimental Obstetrics & Gynecology  2017, Vol. 44 Issue (3): 392-394    DOI: 10.12891/ceog3245.2017
Original Research Previous articles | Next articles
Cytogenetic analysis of 10,286 cases with male infertility
H. Chen1, 2, X. Gao2, L.L. Shi2, X.B. Gao1, *()
1 School of Public Health, Shandong University, Jinan, China
2 Reproductive Hospital Affiliated to Shandong University, Jinan, China
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Abstract  Purpose: Chromosome analysis of 10,286 cases with male infertility and to discuss the genetic causes of male infertility. Materials and Methods: 10,286 patients with azoospermia and oligoasthenozoospermia were collected in the present center from January 2009 to January 2013.Peripheral blood lymphocyte culture and chromosome analysis were performed. Results: In all the 10,286 cases with azoospermia and oligoasthenozoospermia, 8,401 cases showed normal karyotype, 538 cases had chromosome polymorphism, accounting for 5.2% and 1,378 cases had chromosomal abnormalities with a frequency of 13.4%; Conclusions: Genetic factors are closely related to the occurrence of azoospermia and oligoasthenozoospermia, and chromosome analysis in patients with male infertility is necessary.
Key words:  Male infertility      Azoospermia      Oligoasthenozoospermia      Chromosomal abnormality     
Published:  10 June 2017     
*Corresponding Author(s):  X.B. GAO     E-mail:  35282148@qq.com

Cite this article: 

H. Chen, X. Gao, L.L. Shi, X.B. Gao. Cytogenetic analysis of 10,286 cases with male infertility. Clinical and Experimental Obstetrics & Gynecology, 2017, 44(3): 392-394.

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https://ceog.imrpress.com/EN/10.12891/ceog3245.2017     OR     https://ceog.imrpress.com/EN/Y2017/V44/I3/392

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