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Clinical and Experimental Obstetrics & Gynecology  2016, Vol. 43 Issue (6): 905-910    DOI: 10.12891/ceog3191.2016
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Growing teratoma syndrome after ovarian inmature teratoma: a case report and review of the literature
O. Lapuente-Ocamica1, *(), L. Ugarte1, M. Cuadra1, A. Lopez-Picado2, L. Maestro3, I. Lete1
1Obstetrics and Gynecological Unit. Araba University Hospital, Alava
2Araba Research Unit . Araba University Hospital, Alava
3Pathology Department. University Hospital Araba, Vitoria-Gasteiz (Spain)
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Abstract  
Growing teratoma syndrome is an uncommon complication of malignant germ cell cancer, characterised by the development of large tumours during or after chemotherapy, despite normalisation of tumour marker levels and metastasis, which contain only mature teratoma. Given its low incidence, little is data available. The authors present the case of a 15-year-old girl with a growing teratoma and the literature review outlines the current knowledge of its pathogenesis, common sites, diagnosis, natural course, treatment, and prognosis.
Key words:  Growing teratoma syndrome      Immature teratoma      Malignant germ cell tumours     
Published:  10 December 2016     
*Corresponding Author(s):  O. LAPUENTE-OCAMICA     E-mail:  oihane.lapuenteocamica@osakidetza.net

Cite this article: 

O. Lapuente-Ocamica, L. Ugarte, M. Cuadra, A. Lopez-Picado, L. Maestro, I. Lete. Growing teratoma syndrome after ovarian inmature teratoma: a case report and review of the literature. Clinical and Experimental Obstetrics & Gynecology, 2016, 43(6): 905-910.

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https://ceog.imrpress.com/EN/10.12891/ceog3191.2016     OR     https://ceog.imrpress.com/EN/Y2016/V43/I6/905

[1] N. Ohara, K. Teramoto. Ovarian mixed germ cell tumor composed of endodermal sinus tumor and immature teratoma: Case report[J]. Clinical and Experimental Obstetrics & Gynecology, 2000, 27(2): 95-96.
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