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Clinical and Experimental Obstetrics & Gynecology  2016, Vol. 43 Issue (5): 703-707    DOI: 10.12891/ceog3123.2016
Original Research Previous articles | Next articles
Clinical significance of group B streptococcus testing in late pregnancy
Q. Du1, *(), X. Liu1, T. Shi2, J. Long1, W. Ma1, G. Huang1, X. Zhang1
1Clinical Laboratory Department, Sichuan Academy of Medical Sciences & Sichuan Province People's Hospital, Chengdu
2Luzhou Medical College, Luzhou (China)
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Purpose: This study aimed to detect the maternal group B streptococcus (GBS) by real-time PCR method, aiming to understand its germ-carrying situations and clinical significance. Materials and Methods: The secretions of one-third inferior segment of maternal vagina of 1,540 pregnant and postnatal women were collected for GBS detection by real-time PCR method, and the impacts of positive results on the fetus were observed. Results: The detection rate of GBS was 5.6% (86/1540); the premature birth rate of GBS-positive pregnant women was 29.1% (25/86), the miscarriage rate was 19.8% (17/86), the premature rupture rate was 26.7% (23/86), and the fetal distress rate was 24.4% (21/86). Conclusions: The GBS germ-carriers showed increased rates of premature birth, miscarriage, premature rupture, and fetal distress, thus forming adverse effects towards the maternal and infant outcomes.
Key words:  Group B streptococcus (GBS)      Real-time fluorescence PCR      Impacts on mother and child     
Published:  10 October 2016     
*Corresponding Author(s):  Q. DU     E-mail:

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Q. Du, X. Liu, T. Shi, J. Long, W. Ma, G. Huang, X. Zhang. Clinical significance of group B streptococcus testing in late pregnancy. Clinical and Experimental Obstetrics & Gynecology, 2016, 43(5): 703-707.

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