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Clinical and Experimental Obstetrics & Gynecology  2016, Vol. 43 Issue (6): 853-856    DOI: 10.12891/ceog3109.2016
Original Research Previous articles | Next articles
The assessment of maternal and umbilical cord homocysteine levels in obese pregnant women
B. Kaya1, *(), S. Kaya1, H. L. Keskin1, S. Aydoğmuş1, G. Akçay Yegin1, A. Ekiz2, A. F. Avşar3
1Ankara Atatürk Education and Research Hospital, Department of Obstetrics and Gynecology, Ankara
2İstanbul Kanuni Sultan Süleyman Education and Research Hospital, Department of Obstetrics and Gynecology, Istanbul
3Yıldırım Beyazıt University, School of Medicine, Department of Obstetrics and Gynecology, Ankara (Turkey)
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Abstract  
Purpose: The aim of this study was to compare the maternal plasma and umbilical cord blood homocysteine levels in obese and nonobese pregnant women. Materials and Methods: One hundred-ten term pregnant women, who completed their 37th gestational weeks and were not in active labor, were enrolled in the study. While 41 out of them were obese (BMI ≥ 30 kg/m2 ), 69 were non-obese (BMI < 30 kg/m2 ). The maternal plasma and umbilical cord homocysteine levels and umbilical cord pH values were compared between the groups. The statistical analyses were performed using t-test, Mann Whitney test, and Chi-square test. A p < 0.05 value was set as statistically significant. Results: The mean of age was higher in obese group in borderline significance (26.8 ±5.4 vs. 28.8 ±5.1, p = 0.049). The mean of gestational weeks, birthweight, the mode of delivery, and umbilical cord pH values were similar between the groups (p > 0.05). The maternal plasma homocysteine levels [median (interquartile range); 7.6 (4.1) vs. 7.1 (4.9)] and umbilical cord homocysteine values were not statistically different [8.6 (4.2) vs. 8.8 (4.5)] between the groups (p > 0.05). Conclusion: The maternal and umbilical cord blood homocysteine levels are not different in obese and non-obese pregnant women.
Key words:  Pregnancy      Homocysteine      Obesity      Body mass index     
Published:  10 December 2016     
*Corresponding Author(s):  B. KAYA     E-mail:  kayabasak84@gmail.com

Cite this article: 

B. Kaya, S. Kaya, H. L. Keskin, S. Aydoğmuş, G. Akçay Yegin, A. Ekiz, A. F. Avşar. The assessment of maternal and umbilical cord homocysteine levels in obese pregnant women. Clinical and Experimental Obstetrics & Gynecology, 2016, 43(6): 853-856.

URL: 

https://ceog.imrpress.com/EN/10.12891/ceog3109.2016     OR     https://ceog.imrpress.com/EN/Y2016/V43/I6/853

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