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Clinical and Experimental Obstetrics & Gynecology  2016, Vol. 43 Issue (4): 539-543    DOI: 10.12891/ceog3094.2016
Original Research Previous articles | Next articles
Is there an association between serum vitamin D levels and endometrial polyps?
G. Özakşit1, A. Tokmak1, *(), H. Kalkan1, E. Sarıkaya1
1Department of Obstetrics and Gynecology, Dr. Zekai Tahir Burak Women’s Health Education and Research Hospital, Ankara (Turkey)
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Abstract  
Background/Aim: Anti-proliferative effects of vitamin D (VD) had been proposed previously. Herein, the authors aimed to evaluate serum 25(OH)VitD3 levels in women with endometrial polyps (EPs) and to determine whether VD deficiency is a risk factor for EP formation. Materials and Methods: This study was designed as a controlled cross-sectional study. Forty three women with polyps constituted the study group whereas 47 of them constituted the control group. The selection criteria for the study group were hysteroscopic detection and histological confirmation of EPs. The main parameters recorded for each woman were; age, body mass index (BMI), parity, smoking status, co-morbidities, dressing style, dairy intake of VD-rich foods, duration of sunlight exposure, skin photo-type, serum levels of 25(OH)VitD3, calcium, phosphor, and albumin. Results: The mean serum 25(OH)VitD3 level was 8.3±7.7 ng/ml in the study group and 9.3 ± 10.2 ng/ml in the control group (p = 0.583). Mean BMI was statistically significantly higher in the study group (p = 0.003). Logistic regression model showed that only significant risk factor for EPs was increased BMI (OR=1.241; 95% CI = 1.070-2.440; p = 0.004). Conclusion: VD deficiency is common among the reproductive age women and obesity is the most important risk factor for polyp formation. The authors believe that there is no relation between VD and EPs.
Key words:  Endometrial polyps      Risk factors      Vitamin D     
Published:  10 August 2016     
*Corresponding Author(s):  A. TOKMAK     E-mail:  aytekintokmak@gmail.com

Cite this article: 

G. Özakşit, A. Tokmak, H. Kalkan, E. Sarıkaya. Is there an association between serum vitamin D levels and endometrial polyps?. Clinical and Experimental Obstetrics & Gynecology, 2016, 43(4): 539-543.

URL: 

https://ceog.imrpress.com/EN/10.12891/ceog3094.2016     OR     https://ceog.imrpress.com/EN/Y2016/V43/I4/539

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