Please wait a minute...
Clinical and Experimental Obstetrics & Gynecology  2015, Vol. 42 Issue (4): 485-489    DOI: 10.12891/ceog1876.2015
Original Research Previous articles | Next articles
Effect of maternal cervical bacterial colonization on neonatal outcome in high-risk pregnancies: results from a tertiary maternity center in Turkey
M.Y. Oncel1, *(), S. Celen2, G. Demirel1, F.E. Canpolat1, E. Calisici1, R. Ozdemir1, S.S. Oguz1, S. Saygan3, N. Danisman2, U. Dilmen1, 4
1Division of Neonatology, Zekai Tahir Burak Maternity Teaching Hospital, Ankara
2Division of Perinatology, Zekai Tahir Burak Maternity Teaching Hospital, Ankara
3Division of Microbiology, Zekai Tahir Burak Maternity Teaching Hospital, Ankara
4Yıldırım Beyazıt University, School of Medicine, Department of Pediatrics, Ankara (Turkey)
Download:  PDF(126KB)  ( 11 )
Export:  BibTeX | EndNote (RIS)      
Abstract  
Purpose: To evaluate and compare the morbidity and mortality of neonates born to pregnant women with positive and negative cervical cultures. Materials and Methods: The demographic and clinical features of mothers included in this study, along with details of the microorganisms isolated on maternal cervical cultures and the number of days between a positive cervical culture and delivery were recorded. Neonates were stratified into two groups based on cervical culture results of their mothers - Group 1, positive cervical culture; Group 2, negative cervical culture. Results: A total of 216 women who delivered 242 infants were included in the study. Group 1 consisted of 90 neonates while Group 2 had 152 newborns. The difference between the groups with demographic characteristics was statistically insignificant. Mean levels of the acute phase reactants, CRP, and IL-6, obtained six hours after delivery were significantly higher in Group 1 compared to Group 2 (p < 0.05 for C-reactive protein (CRP) and p < 0.001 for IL-6). Although there was no difference between groups in terms of duration of respiratory support, mean duration of hospitalization, as well as mortality rate were significantly higher in Group 1 (p < 0.001, p < 0.05, respectively). Conclusions: Women diagnosed with a high-risk pregnancy should be treated with antibiotics immediately after a positive cervical culture result, and delivery should be delayed until the success of antibiotic treatment can be evaluated. Early initiation of maternal antibiotic therapy is associated with shorter durations of hospital stay for newborns. Close follow-up of mothers with high-risk pregnancies and extension of treatment duration are critical for determining prognosis in newborn infants.
Key words:  Cervical bacterial colonization      Maternal antibiotic therapy      Neonatal outcome     
Published:  10 August 2015     
*Corresponding Author(s):  M.Y. ONCEL     E-mail:  dryekta@gmail.com

Cite this article: 

M.Y. Oncel, S. Celen, G. Demirel, F.E. Canpolat, E. Calisici, R. Ozdemir, S.S. Oguz, S. Saygan, N. Danisman, U. Dilmen. Effect of maternal cervical bacterial colonization on neonatal outcome in high-risk pregnancies: results from a tertiary maternity center in Turkey. Clinical and Experimental Obstetrics & Gynecology, 2015, 42(4): 485-489.

URL: 

https://ceog.imrpress.com/EN/10.12891/ceog1876.2015     OR     https://ceog.imrpress.com/EN/Y2015/V42/I4/485

[1] Ugo Indraccolo, Maria Giulia Lombana Marino, Beatrice Bianchi, Silvia Catagini, Danila Morano, Pantaleo Greco. Symphysis-fundal height correlates with adverse delivery and neonatal outcomes in induced full-term and premature pregnancies[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(3): 637-641.
[2] M. Collict, Y. Mucat Baron, M. Gatt, N. Calleja. Advanced maternal age and neonatal outcomes in Malta[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(2): 265-269.
[3] I. Babović, M. Matić, S. Plešinac. Woman with Marfan syndrome in pregnancy: good maternal and fetal outcome – a case report and literature review[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(6): 920-923.
[4] K.P. Fuller, S. DeGroff, A.F. Borgida. Neonatal outcomes based on antenatal corticosteroid exposure time for infants delivered between 23 and 34 weeks gestation[J]. Clinical and Experimental Obstetrics & Gynecology, 2017, 44(2): 247-251.
[5] Y. Cakiroglu, E. Doger, S. Yildirim Kopuk, A. Gunlemez, D. Oguz, E. Caliskan. Does amnioreduction increase success of emergency cervical cerclage in cases with advanced cervical dilatation and protruding membranes?[J]. Clinical and Experimental Obstetrics & Gynecology, 2016, 43(5): 708-712.
[6] N. Aka, Ş. Arpacı, F. Vura, G. Köse. Perinatal and neonatal outcomes of maternal heart diseases[J]. Clinical and Experimental Obstetrics & Gynecology, 2016, 43(4): 560-564.
[7] M. Soilemetzidis, P. Pinidis, N. Tsagias, A. Ammari, A. Liberis, V. Liberis, G. Galazios, P. Tsikouras. The effectiveness of misoprostol or dinoprostone in neonatal outcome after labour induction in post-term nulliparas[J]. Clinical and Experimental Obstetrics & Gynecology, 2015, 42(5): 649-652.
[8] G. Pados, M. Zafrakas, D. Tsolakidis, E. Assimakopoulos, H. Bili, B.C. Tarlatzis. Obstetric and neonatal outcome after assisted fertilization and spontaneous conception: a comparative study[J]. Clinical and Experimental Obstetrics & Gynecology, 2012, 39(4): 448-451.
[9] I. Babovic, S. Plesinac. Doppler examination in the evaluation of outcomes in pregnancies complicated by gestational hypertension and fetal intrauterine growth retardation - is it enough?[J]. Clinical and Experimental Obstetrics & Gynecology, 2012, 39(2): 222-224.
[10] D. Eroglu, M. Oktem, F. Yanik, E. Kuscu. Labor induction at term: a comparison of the effects of 50 μg and 25 μg vaginal misoprostol[J]. Clinical and Experimental Obstetrics & Gynecology, 2007, 34(2): 102-105.
[11] R. Axt, M. Hippach, D. Mink, H. J. Hendrik, A. K. Ertan, W. Schmidt. Maternal and neonatal outcome in a monochorionic twin pregnancy complicated by single intrauterine demise[J]. Clinical and Experimental Obstetrics & Gynecology, 1999, 26(3-4): 155-157.
[12] F. Diani, S. Venanzi, G. Zanconato, S. Murari, C. Moscatelli, A. Torinetto. Fetal macrosomia and management of delivery[J]. Clinical and Experimental Obstetrics & Gynecology, 1997, 24(4): 212-214.
[13] A. Restaino, C. Campobasso A. D’Aloya, A. D. Abbruzzese, A. Valerio F. Pansini. Cirrhosis and pregnancy[J]. Clinical and Experimental Obstetrics & Gynecology, 1996, 23(4): 236-239.
[14] M. BRESADOLA, F. LO MASTRO, V. ARENA, L. BELLAVEGLIA, F. SCARPELLINI. Preterm labour and neonatal parameters[J]. Clinical and Experimental Obstetrics & Gynecology, 1995, 22(3): 235-239.
No Suggested Reading articles found!