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Clinical and Experimental Obstetrics & Gynecology  2014, Vol. 41 Issue (4): 478-482    DOI: 10.12891/ceog18122014
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Sympathomimetic amine therapy found effective for treatment of refractory chronic complex regional pain syndrome (reflex sympathetic dystrophy)
J.H. Check1, *(), R. Cohen2
1Cooper Medical School of Rowan University, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Camden, New Jersey
2Philadelphia College of Osteopathic Medicine, Department of Obstetrics and Gynecology, Philadelphia, Pennsylvania (USA)
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Abstract  
Purpose: To determine if treatment with sympathomimetic amines could improve the pain from complex regional pain disorder (CRPD) which was keeping a woman from trying to conceive her second child. Materials and Methods: Dextroamphetamine sulfate was prescribed. Results: Within a short length of time the woman’s wrist pain considerably improved to the point that she is ready to try in vitro fertilization once again to have a second baby. Conclusions: Though sympathomimetic amines are used by some reproductive endocrinologists for unexplained infertility and unexplained recurrent miscarriages, the most common use by the gynecologist is for pelvic pain. Despite the thought by some clinicians and researchers that the etiology for CRPD may be related to sympathetic nervous system hyperactivity (and thus sympathomimetic amines could theoretically exacerbate the symptoms), in fact, the treatment with dextroamphetamine sulfate may turn out to be a new and possibly the most effective, least risky, and least expensive treatment to date for CRPD.
Key words:  Complex regional pain syndrome      Reflex sympathetic dystrophy      Sympathomimetic amines      Dextroamphetamine sulfate     
Published:  10 August 2014     
*Corresponding Author(s):  J.H. CHECK     E-mail:  laurie@ccivf.com

Cite this article: 

J.H. Check, R. Cohen. Sympathomimetic amine therapy found effective for treatment of refractory chronic complex regional pain syndrome (reflex sympathetic dystrophy). Clinical and Experimental Obstetrics & Gynecology, 2014, 41(4): 478-482.

URL: 

https://ceog.imrpress.com/EN/10.12891/ceog18122014     OR     https://ceog.imrpress.com/EN/Y2014/V41/I4/478

[1] J.H. Check, D. Check, R. Cohen. A novel effective treatment for menière’s disease – dextroamphetamine sulfate[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(5): 807-809.
[2] J.H. Check, D. Check. The increased cellular permeability syndrome manifesting as severe idiopathic type urinary incontinence[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(5): 812-814.
[3] J.H. Check, R. Cohen. Sympathomimetic amine therapy abrogates severe long-term unexpalined abdominal pain and diarrhea (microscopic colitis) - possible infertility implications[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(3): 489-491.
[4] J.H. Check, D.L. Check, M.P. Dougherty. Marked improvement of the aromatase induced arthralgia syndrome following treatment with dextroamphetamine sulfate[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(2): 291-292.
[5] J.H. Check, M.P. Dougherty, D.L. Check. Long standing post-herpetic neuralgia resistant to standard anti-neuropathy medication showing quick dramatic improvement following treatment with sympathomimetic amines[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(2): 335-336.
[6] J.H. Check, M. Citerone, T. Citerone. The increased cellular permeability syndrome as a cause of traumatic stuttering[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(5): 773-774.
[7] J.H. Check. Changing the name of a syndrome: sympathetic neural hyperalgesia edema syndrome becomes – the increased cellular permeability syndrome[J]. Clinical and Experimental Obstetrics & Gynecology, 2017, 44(6): 819-823.
[8] J.H. Check, R. Cohen. Amelioration of severe generalized idiopathic pruritus in an estrogen deficient woman taking an aromatase inhibitor for breast cancer following treatment with amphetamine salts[J]. Clinical and Experimental Obstetrics & Gynecology, 2017, 44(6): 934-935.
[9] J. H. Check, R. Cohen. Marked improvement of severe gastroparesis following high dosage, but very well tolerated, dextroamphetamine sulfate[J]. Clinical and Experimental Obstetrics & Gynecology, 2017, 44(4): 611-612.
[10] J.H. Check, A. Jaffe. Dextroamphetamine sulfate provided quick relief of severe post-partum depression that was recalcitrant to standard antidepressants and psychotherapy[J]. Clinical and Experimental Obstetrics & Gynecology, 2017, 44(2): 272-274.
[11] J.H. Check. Chronic unremitting lower abdominal pain quickly abrogated following treatment with amphetamine[J]. Clinical and Experimental Obstetrics & Gynecology, 2016, 43(1): 109-111.
[12] J.H. Check. Dextroamphetamine sulfate treatment eradicates long-term chronic severe headaches from temporomandibular joint syndrome - a case that emphasizes the role of the gynecologist in treating headaches in women[J]. Clinical and Experimental Obstetrics & Gynecology, 2016, 43(1): 119-122.
[13] J.H. Check, A. Jaffe. Resolution of pelvic pain related to adenomyosis following treatment with dextroamphetamine sulfate[J]. Clinical and Experimental Obstetrics & Gynecology, 2015, 42(5): 671-672.
[14] J.H. Check, R. Cohen. Complete resolution of frozen shoulder syndrome in a woman treated with dextroamphetamine sulfate for chronic urinary urgency[J]. Clinical and Experimental Obstetrics & Gynecology, 2015, 42(5): 679-680.
[15] J. H. Check, R. Cohen. An update on the treatment of female alopecia and the introduction of a potential novel therapy[J]. Clinical and Experimental Obstetrics & Gynecology, 2015, 42(4): 411-415.
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