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Clinical and Experimental Obstetrics & Gynecology  2015, Vol. 42 Issue (4): 529-530    DOI: 10.12891/ceog1778.2015
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Failed surgical therapy for chronic back pain and sciatica may be due to hypofunction of the sympathetic nervous system
J.H. Check1, 2, *(), A. Whetstone3
1The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, Cooper Hospital/University Medical Center Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Camden, NJ
2Cooper Medical School of Rowan University, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Camden, NJ
3The University of Medicine and Dentistry of New Jersey, School of Osetopathic Medicine, Camden, NJ (USA)
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Abstract  
Purpose: To describe a distinctive pharmacological treatment for chronic pelvic pain and sciatica after spinal surgery with a laminectomy and spinal fusion failed to provide relief. Materials and Methods: Dextroamphetamine suflate was prescribed to a woman with a history of chronic back pain which was attributed to a ruptured disc. The pain was still unbearable after surgery. Results: After adjusting dosage, within three months of the correct dose, 25 mg twice a day, relief was provided and has persisted for ten months. Conclusions: Chronic pelvic pain and sciatica both may be symptoms of hypofunction of the sympathetic nervous system. In addition, with other pain symptoms, this can be effectively treated with sympathomimetic amines.
Key words:  Backache      Sciatica      Sympathomimetic amines      Sympathetic hypofunction      Discectomy     
Published:  10 August 2015     
*Corresponding Author(s):  J.H. CHECK     E-mail:  laurie@ccivf.com

Cite this article: 

J.H. Check, A. Whetstone. Failed surgical therapy for chronic back pain and sciatica may be due to hypofunction of the sympathetic nervous system. Clinical and Experimental Obstetrics & Gynecology, 2015, 42(4): 529-530.

URL: 

https://ceog.imrpress.com/EN/10.12891/ceog1778.2015     OR     https://ceog.imrpress.com/EN/Y2015/V42/I4/529

[1] J.H. Check. Changing the name of a syndrome: sympathetic neural hyperalgesia edema syndrome becomes – the increased cellular permeability syndrome[J]. Clinical and Experimental Obstetrics & Gynecology, 2017, 44(6): 819-823.
[2] J. H. Check, R. Cohen. Marked improvement of severe gastroparesis following high dosage, but very well tolerated, dextroamphetamine sulfate[J]. Clinical and Experimental Obstetrics & Gynecology, 2017, 44(4): 611-612.
[3] J.H. Check. Chronic unremitting lower abdominal pain quickly abrogated following treatment with amphetamine[J]. Clinical and Experimental Obstetrics & Gynecology, 2016, 43(1): 109-111.
[4] J.H. Check. Dextroamphetamine sulfate treatment eradicates long-term chronic severe headaches from temporomandibular joint syndrome - a case that emphasizes the role of the gynecologist in treating headaches in women[J]. Clinical and Experimental Obstetrics & Gynecology, 2016, 43(1): 119-122.
[5] J.H. Check, A. Jaffe. Resolution of pelvic pain related to adenomyosis following treatment with dextroamphetamine sulfate[J]. Clinical and Experimental Obstetrics & Gynecology, 2015, 42(5): 671-672.
[6] J.H. Check, R. Cohen. Complete resolution of frozen shoulder syndrome in a woman treated with dextroamphetamine sulfate for chronic urinary urgency[J]. Clinical and Experimental Obstetrics & Gynecology, 2015, 42(5): 679-680.
[7] J. H. Check, R. Cohen. An update on the treatment of female alopecia and the introduction of a potential novel therapy[J]. Clinical and Experimental Obstetrics & Gynecology, 2015, 42(4): 411-415.
[8] J.H. Check, J. Weidner. The confounding effect of the development of idiopathic orthostatic edema and thyrotoxcosis on weight fluctuation related to effects on free water clearance in a woman with long-standing surgically induced panhypopituitarism and diabetes insipidus[J]. Clinical and Experimental Obstetrics & Gynecology, 2015, 42(3): 376-377.
[9] J.H. Check, R. Cohen. Marked improvement of vulvovaginitis of unknown origin in a pediatric patient - case report[J]. Clinical and Experimental Obstetrics & Gynecology, 2014, 41(6): 723-724.
[10] J.H. Check, R. Cohen. The triad of luteal phase ocular migraines, interstitial cystitis, and dyspareunia as a result of sympathetic nervous system hypofunction[J]. Clinical and Experimental Obstetrics & Gynecology, 2014, 41(5): 575-577.
[11] J. Weidner, J.H. Check. Marked improvement of the autoimmune syndrome associated with autoimmune hepatitis by treatment with sympathomimetic amines[J]. Clinical and Experimental Obstetrics & Gynecology, 2014, 41(4): 460-461.
[12] J.H. Check, R. Cohen. Sympathomimetic amine therapy found effective for treatment of refractory chronic complex regional pain syndrome (reflex sympathetic dystrophy)[J]. Clinical and Experimental Obstetrics & Gynecology, 2014, 41(4): 478-482.
[13] C.P. Potestio, J.H. Check, J. Mitchell-Williams. Improvement in symptoms of the syndrome of mitochondrial encephalopathy, lactic acidosis, and stroke-like symptoms (MELAS) following treatment with sympathomimetic amines – possible implications for improving fecundity in women of advanced reproductive age[J]. Clinical and Experimental Obstetrics & Gynecology, 2014, 41(3): 343-345.
[14] J.H. Check, S. Chan. Complete eradication of chronic long standing eczema and keratosis pilaris following treatment with dextroamphetamine sulfate[J]. Clinical and Experimental Obstetrics & Gynecology, 2014, 41(2): 202-204.
[15] J.H. Check, R. Cohen. Severe headaches from intracranial hypertension (pseudotumor cerebri) abrogated by treatment with dextroamphetamine sulfate[J]. Clinical and Experimental Obstetrics & Gynecology, 2014, 41(2): 211-213.
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