Please wait a minute...
Clinical and Experimental Obstetrics & Gynecology  2014, Vol. 41 Issue (5): 556-560    DOI: 10.12891/ceog17692014
Original Research Previous articles | Next articles
Fetal nasal bone length at 11+0- 13+6 weeks of gestation: an evaluation of 554 consecutive cases
A. Cansu1, H. Ozgur1, S. Guven2, *(), G. Dinc3, H. Dinc1
1Department of Radiology, Karadeniz Technical University Faculty of Medicine, Trabzon
2Department of Obstetrics and Gynecology, Karadeniz Technical University Faculty of Medicine, Trabzon
3Clinic of Obstetrics and Gynecology, Trabzon Women and Children Hospital, Trabzon (Turkey)
Download:  PDF(108KB)  ( 7 )
Export:  BibTeX | EndNote (RIS)      
Abstract  
Purpose of investigation: To develop a nomogram for estimating nasal bone length (NBL) at 11+0- 13+6 weeks of gestation in 554 consecutive cases and to determine the value of NBL measurement in screening for chromosomal abnormalities. Materials and Methods: NBL and crown-rump length (CRL) were examined in 554 fetuses at 11+0-13+6 weeks’ gestation. A nomogram for NBL was developed with data from 479 healthy fetuses in which fetal profile examination was possible. Reference values, including percentiles, were calculated for each gestational age. Result: A linear correlation was noted between CRL and NBL in healthy fetuses at 11+0-11+6, 12+0-12+6 and 13+0-13+6 weeks of gestation. Mean NBL was 2.18 ± 0.53 mm, 2.46 ± 0.45 mm, and 2.91 ± 0.55 mm in healthy fetuses, for these time frames, respectively. NBL increased significantly with CRL from respective means of 2.26 ± 0.43, 2.60 ± 0.48, 2.77 ± 0.43, and 3.16 ± 0.52 mm at 45 - 54.9, 55 - 64.9, 65 - 74.9, and 75 - 84 mm. Conclusion: The authors developed a NBL nomogram with data from normal, healthy Turkish fetuses at 11+0-13+6 weeks of gestation. These reference ranges may prove useful in prenatal screening and diagnosis of syndromes known to be associated with nasal hypoplasia.
Key words:  Fetal nasal bone      Ultrasonography      Chromosomal abnormalities     
Published:  10 October 2014     
*Corresponding Author(s):  S. GUVEN     E-mail:  drsuleymanguven@yahoo.com

Cite this article: 

A. Cansu, H. Ozgur, S. Guven, G. Dinc, H. Dinc. Fetal nasal bone length at 11+0- 13+6 weeks of gestation: an evaluation of 554 consecutive cases. Clinical and Experimental Obstetrics & Gynecology, 2014, 41(5): 556-560.

URL: 

https://ceog.imrpress.com/EN/10.12891/ceog17692014     OR     https://ceog.imrpress.com/EN/Y2014/V41/I5/556

[1] Anjeza Xholli, Anna Biasioli, Giovanni Grandi, Angelo Cagnacci. Dienogest-based hormonal contraception induced changes in the ultrasound presentation of the uterus and menstrual pain[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(5): 1186-1192.
[2] Özgür Koçak, Cem Koçak. Finding the best formulas to estimate fetal weight based on ultrasound for the Turkish population: a comparison of 24 formulas[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(3): 676-685.
[3] Saša Raičević, Duško Kljakić, Filip Vukmirović, Miloš Z. Milosavljević. A giant placental chorioangioma with a resultant live birth; a discussion of management options[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(2): 426-430.
[4] Xiao-Hua Li, Jian-Kun Zhou, Jing-Dan Cheng. Application of ultrasound in hepatic pregnancy: a case report and literature review[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(2): 434-438.
[5] Y. Wang, X.Y. Lu, F. Xu, H.M. Huang, Y. Xu, X.W. Xi. Detection of uterine artery hemodynamic changes in patients with gestational hypertension based on Doppler ultrasonography[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(4): 584-589.
[6] M. Özsürmeli, M. Sucu, E. Arslan, S. Büyükkurt. Perinatal outcome of fetuses with echogenic intracardiac focus[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(3): 372-375.
[7] E.H. Comert, H. Sal, C. Kart, E.S. Guvendag Guven, S. Guven. Prenatal diagnosis of fetal gallbladder duplication associated with uncommon chromosomal anomaly (46, XX, t(X;10) (p11.2;q24.3) [20])[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(6): 980-981.
[8] G. Capobianco, S. Mantegna, M. Farina, O.E. Gallo, C. Pini, E. Tinacci, P.L. Cherchi, S. Dessole. Saline infusion sonography: technique, advantages and limits for the study of uterus and fallopian tubes. Review and care pathway[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(4): 531-538.
[9] J.-E. Park, H.-H. Cha, W. J. Seong. Congenital unilateral pulmonary hypoplasia presenting as cardiac dextroposition on prenatal ultrasonography[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(1): 171-173.
[10] Turgut Aydin, Huseyin Aksoy, Ozge Idem Karadag, Ulku Aksoy, Elif Cinar. A comparative study on therapeutic outcomes and clinical implications of transvaginal and transabdominal guidance during embryo transfer[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(6): 823-827.
[11] Shigeo Iijima. A case of body stalk anomaly: the value of adding fetal magnetic resonance imaging to ultrasonography for perinatal management[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(6): 930-932.
[12] Sun Young Jung, Yong Teak Oh, Suk Young Kim. Predict pregnancy outcomes of prenatal megaureter by prenatal ultrasonography[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(4): 544-548.
[13] Lieming Wen, Qichang Zhou, Shi Zeng. Gestational progression and blood supply assessment of a six-week primary hepatic pregnancy[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(4): 594-596.
[14] Sun Young Jung, Suk Young Kim. Is it possible to early diagnose uterine rupture by ultrasound without common clinical signs during pregnancy following laparoscopic myomectomy?[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(4): 605-607.
[15] D.I. Zoričić, A.L. Despot, A. Lj. Tikvica Luetić, D.L. Belci, D.I. Bečić, Z.M. Protrka, P.S. Arsenijevic, A.B. Dimitrijević. Three-dimensional reconstructed coronal plane in detection and differentiation of congenital uterine malformations[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(3): 361-366.
No Suggested Reading articles found!