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Clinical and Experimental Obstetrics & Gynecology  2014, Vol. 41 Issue (5): 499-506    DOI: 10.12891/ceog16592014
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Association of sympathetic nervous system activity with polycystic ovarian syndrome
W. Li1, Y. Chen1, L. Xu1, *()
1Department of Obstetrics and Gynecology, West China Women’s and Children’s Hospital of Sichuan University, Chengdu (China)
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Abstract  
Polycystic ovary syndrome (PCOS) is a disease with high prevalence which has various clinical manifestations and increased risk of long-term complications, such as dyslipidemia, diabetes, metabolic syndrome, and hormone related tumor. However, the etiology of PCOS is still unclear. Consequently, the effect of symptomatic treatment is not always satisfactory and the prognosis is also unpredictable. Currently, commonly psychological syndromes and imbalance of sympathetic neuroendocrine system have been found in PCOS population, and increasing evidence highlighted the hypothesis that characteristics of PCOS could be partially explained by the instability of the sympathetic nervous system (SNS). Furthermore, surgical intervention of animal trials in order to normalize SNS could improve symptoms of PCOS. This review attempted to clarify the relationship between SNS and PCOS development and then discuss the possible new therapies in PCOS treatment via regulating the SNS.
Key words:  Sympathetic nervous system      Polycystic ovary syndrome      PCOS     
Published:  10 October 2014     
*Corresponding Author(s):  L. XU     E-mail:  liangzxu@126.com

Cite this article: 

W. Li, Y. Chen, L. Xu. Association of sympathetic nervous system activity with polycystic ovarian syndrome. Clinical and Experimental Obstetrics & Gynecology, 2014, 41(5): 499-506.

URL: 

https://ceog.imrpress.com/EN/10.12891/ceog16592014     OR     https://ceog.imrpress.com/EN/Y2014/V41/I5/499

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