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Clinical and Experimental Obstetrics & Gynecology  2014, Vol. 41 Issue (1): 72-74    DOI: 10.12891/ceog16342014
Original Research Previous articles | Next articles
Biomarkers of peritoneal fluid in endometriosis identified by surface-enhanced laser desorption/ionization time-of-flight
L. Wang1, X.Y. Ding1, J.K. Yu2, S.Z. Zhang2, W. Zheng1, *()
1The 2nd Affiliated Hospital, Department of Gynecology, and Ministry of Education Key Laboratory of Cancer Prevention and Intervention, Zhejiang University School of Medicine, Hangzhou
2The 2nd Affiliated Hospital, Cancer institute, and Ministry of Education Key Laboratory of Cancer Prevention and Intervention, Zhejiang University School of Medicine, Hangzhou (China)
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Abstract  
Objectives: This work aims to detect the peritoneal fluid proteomic patterns in endometriosis patients, build diagnostic models, and evaluate its clinical significance. Study Design: The authors used SELDI-TOF-MS protein chip array technology to detect biomarkers of peritoneal fluid in endometriosis patients. Fourteen endometriosis patients and 16 persons without endometriosis as control group were tested. Results: Four potential biomarkers (4428m/z, 6891m/z, 13766m/z, and 6427m/z) were found. Conclusions: This method showed great potential in screening better biomarkers for endometriosis.
Key words:  Endometriosis      Peritoneal fluid      Surface-enhanced laser desorption/ionization time-of-flight      Biomarkers      adenomyosis     
Published:  10 February 2014     
*Corresponding Author(s):  W. ZHENG     E-mail:  weizhengcn@126.com

Cite this article: 

L. Wang, X.Y. Ding, J.K. Yu, S.Z. Zhang, W. Zheng. Biomarkers of peritoneal fluid in endometriosis identified by surface-enhanced laser desorption/ionization time-of-flight. Clinical and Experimental Obstetrics & Gynecology, 2014, 41(1): 72-74.

URL: 

https://ceog.imrpress.com/EN/10.12891/ceog16342014     OR     https://ceog.imrpress.com/EN/Y2014/V41/I1/72

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